TABLE 7-41 Common Side Effects of Chemotherapeutic Agents

Nausea and Vomiting

Mucositis

Diarrhea

Skin Reactions

Lung

Neurological

Alkylating Agents

Busulfan

0

0

Hyperpigmentation

0

0

Carboplatin

0

0

0 Alopecia

0

0

Cisplatin

0

0

0

Chlorambucil

0

0

0

0

0

Cyclophosphamide

+

0

0

0

0

DT1C

4-

0

0

0

0

0

Ifosfamide

0

0

Alopecia

0

Encephalopathy

Mechlorethamine

Alopecia, rash

0

0

Melphalan

0

0

0

0

0

0

Antimetabolites

Cytosine arabinoside

0

0

0

0

Fhidarabine

+

0

0

0

0

0

5-Fluorouracil

0

+

Phlebitis

0

Cerebellar

Hydroxyurea

0

0

0

Skin atrophy

0

0

Methotrexate

4-

4«

Dermatitis

0

with leucovorin

+

4-

Dermatitis

0

2-Deoxycoformycin

0

0

Erythema

0

Lethargy, coma

6-Mercaptopurine

0

0

Rash

0

0

Thioguanine

0

0

0

0

2-Chlorodeoxyadenosinc

+

0

0

0

0

0

Antitumor Antibiotics

Bleomycin

0

0

0

Erythema

0

Dactinomycin

Alopecia, rash

0

0

Daunorubicin

+

Alopecia, vesicant

0

0

Doxorubicin

4-

Alopecia, vesicant

0

0

Idarubicin

4-

Alopecia, vesicant

0

0

Mitomycin C

0

Vesicant

0

Mitoxantrone

+

+

+

Alopecia, vesicant

0

0

Nitrosoureas

Carmustine (BCNU)

0

0

0

0

Lomustine (CCNU)

0

0

0

0

0

Streptozocin

0

0

0

0

0

Thiotepa

+

+

+

Alopecia, rash

0

0

Plant Alkaloids

Etoposide

0

0

0

0

0

0

Vinblastine

0

Alopecia, vesicant

0

Vincristine

0

0

0

Vesicant

0

+ Neuropathy

Taxol

+

0

0

Alopecia

0

Neuropathy