ANTINEOPLASTIC DRUG CLASSIFICATIONS

Antineoplastic Drug Classifications

  1. Alkylating agents
    1. Alkyl sulfonates
      1. Busulfan (Myleran)
    2. Ethylenimines
      1. Thiotepa
    3. Nitrosoureas
      1. Carmustine (BCNU, BiCNU)
      2. Lomustine (CCNU, CeeNu)
      3. Semustine (methyl-CCNU)
      4. Streptozocin (Zanosar, streptozotocin)
    4. Nitrogen mustards
      1. Mechlorethamine hydrochloride (Mustargen, HN2, nitrogen mustard)
      2. Cyclophosphamide (Cytoxan)
      3. Chlorambucil (Leukeran)
      4. Melphalan (Alkeran, L-PAM, L-phenylalanine mustard)
      5. Ifosfamide (Ifex)
    5. Triazenes
      1. Dacarbazine (DTIC-Dome)

  2. Antibiotics
    1. Anthracyclines
      1. Doxorubicin hydrochloride (Adriamycin)
      2. Daunorubicin (daunomycin, Cerubidine)
      3. Idarubicin (Idamycin)
    2. Bleomycins
        3. Bleomycin sulfate (Blenaxane)
    3. Dactinomycin (actinomycin D, Cosmegen)
    4. Mitomycin (mitomycin C, Mutamycin)
    5. Plicamycin (Mithracin)

  3. Antimetabolites
    1. Folate antagonist
      1. Methotrexate (Folex, Mexate)
    2. Purine analogues
      1. Thioguanine (6-TG, 6-thioguanine)
      2. Mercaptopurine (6-MP, Purinethol)
      3. Fludarabine (Fludara)
      4. Pentostatin (deoxycoformycin, Nipent)
      5. Cladribine (2-chloro-deoxyadenosine, Leustatin)
    3. Pyrimidine analogues
      1. Cytarabine (cytosine arabinoside, Cytosar-U, ara-C)
      2. Fluorouracil (5-FU, 5-fluorouracil)

  4. Cellular growth factors
    1. Filgrastim (Neupogen)
    2. Sargramostim (Leukine, Prokine)
  5. Enzymes
    1. L-Asparaginase (Elspar)

  6. Hormonal agents
    1. Androgens/antiandrogens
      1. Flutamide (Eulexin)
    2. Estrogens/antiestrogens
      1. Tamoxifen citrate (Nolvadex)
      2. Estramustine phosphate sodium (Emcyt)
    3. Glucocorticoids
    4. Luteinizing hormone-releasing hormone (LH-RH) antagonists
      1. Buserelin (Suprefact)
      2. Leuprolide (Lupron)
    5. Octreotide acetate (Sandostatin)

  7. Immunomodulating agents
    1. Levamisole (Ergamisol)
    2. Interferons
      1. Interferon alfa-2a (Roferon-A)
      2. Interferon alfa-2b (Intron A)
    3. Interleukins: aldesleukin (interleukin-2, IL-2, Proleukin)

  8. Miscellaneous agents
    1. Carboplatin (Paraplatin)
    2. Cisplatin (cis-platinum II, Platinol)
    3. Hexamethylmelamine (HMM)
    4. Hydroxyurea (Hydrea)
    5. Mitotane (o,p'-DDD, Lysodren)
    6. Mitoxantrone (Novantrone)
    7. Procarbazine (N-methylhydrazine, Matulane, Natulan)

  9. Monoclonal antibodies

  10. Plant-derived products
    1. Vinca alkaloids
      1. Vincristine (Oncovin)
      2. Vinblastine (Velban)
    2. Epipodophyllotoxins
      1. Etoposide (Vepesid)
      2. Teniposide (Vumon)
    3. Taxanes: paclitaxel (Taxol)